Eat Healthy And Move More!

Cisplatin, pentamidine, and foscarnet. Mg deficiency is seen frequently in

Alcoholics and diabetic patients. Many of these factors may be present

Simultaneously in ICU patients. For example, many ICU patients receive Mg-free

Intravenous fluids and/or total parenteral nutrition, and acute tubular necrosis

Often occurs in patients the ICU. Trauma patients are frequently treated with

Antibiotics, often including aminoglycosides.

Factors associated with hypophosphatemia include nasogastric suction, liver

Disease, sepsis, alcoholism, and acidosis associated with diabetic ketoacidosis.

Various drugs such as P-binding antacids, catecholamines, beta-adrenergic

Agonists, Na bicarbonate, acetazolamide, and (when administered via a

Gastro-tube) sucralfate can contribute significantly to the development of

Hypophosphatemia [16]

. Also, refeeding hypophosphatemia after starvation for a period as short as 48

Hrs occurs commonly in critically ill patients in the ICU [17]

. Poor nutritional status predisposes to this syndrome. Thus, as with

Hypomagnesemia, a combination of many factors may put ICU patients at risk for

Hypophosphatemia. Polyuresis induced by cerebral injury increases this risk even

Further, as demonstrated by the results of our study. Hypophosphatemia is

Associated with weakness of respiratory muscles [11][12][13]

, respiratory infections [12]

, and ventricular tachycardia [14]

. Thus, clinical outcome in ICU patients may be adversely affected by


The mechanism through which patients with severe head injury could be put at

Risk for the development of electrolyte disorders is unclear. A shift of

Electrolytes from the extracellular to the intracellular compartment may have

Taken place; electrolyte loss through induction of polyuresis by cerebral injury.